Did you realize that within a very small section of skin, you have various nerve cells. Some cells only ‘light up’ or work when you apply pressure. Some are sensitive to temperature. Some are sensitive only to pain. The nerve cells which are sensitive to pain are called nociceptor cells.
Currently, no drug works directly on nociceptor cells; but on nerve pathways which lead to the nociceptor cells. Or a drug may work on all the different types of cells, not solely nociceptor pain cells. Or a drug may totally anesthetize you, in which case you are paralyzed, unconscious, and pain free.

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