Diagnosing and Testing for Non-Hodgkin's Lymphoma

According to the Mayo Clinic, a doctor may use the following procedures to help diagnose non-Hodgkin's lymphoma:

  • Physical examination
  • Blood and urine tests
  • Imaging techniques
  • Lymph node biopsy
  • Bone marrow biopsy

Doctors classify non-Hodgkin's disease into about 30 types. Besides the differentiation between B cell and T cell types of the disease, classification is based on several other factors, including:

  • Microscopic appearance
  • Cellular genetic changes
  • Cell size
  • Staining patterns with specific antibody stains
  • How the cancer cells group together
  • How fast the cancer grows

Doctors also assign a stage (I through IV) to the disease, based on the number of tumors and how widely the tumors have spread.