Chemo Additive Prolongs Life But At High Mortality Risk

Research reported in the December 14, 2006 edition of the New England Journal of Medicine states that the addition of Avastin (bevacizumab) to chemotherapy for non-squamous cell, non-small-cell lung cancer (NSCLC) increased patient survival by two months, but treatment-related deaths also rose.

The good news is that median survival was 12.3 months in the group that received a Avastin-chemotherapy combination versus 10.3 months for patients randomized to Taxol (paclitaxel) and Paraplatin (carboplatin) alone (P=0.003).

However, the report was not all good news. There were 15 treatment related deaths in the Avastin group versus two in the Taxol/Paraplatin group.


New England Journal of Medicine
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