According to a report in General Dentistry, the Academy of General Dentistry's (AGD) clinical journal, patients taking biphosphonates for Paget's Disease, osteoporosis, multiple myeloma, and bone metastasis from other cancers are at risk for severe jaw disease if dental surgery is performed.
Even having a tooth extracted can lead to a healing problem. Because these drugs last in the bone indefinitely, it is recommended that any necessary surgery take place before starting biphosphonate therapy. At the very least, the dentist should be aware that the patient is taking one of the biphosphonate drugs.

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