Physiological Causes of Migraine

Causes: Physiological Understanding

Migraine is a neurochemical chain reaction that involves 5 distinct phases of a neurological process: prodrome, aura (may or may not be present), mild, moderate, or severe pain, and postdrome. Once the reaction is ‘triggered’ the trigeminovascular system releases chemicals which cause an inflammatory response, perceived as pain. The cascades moves rapidly up the brain stem through the hypothalamus to the cortical regions of the brain. The escalation of pain will last for hours, or even days; incapacitating its victim.


National Headache Organization
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