According to the Mayo Clinic, atherosclerosis is a major cause of aortic aneurysms. Atherosclerosis is the accumulation of fatty deposits and other substances in the arteries. As atherosclerosis worsens, the aortic wall becomes weak or damaged. Over time, the constant pressure of blood coursing through a weakened aorta can cause a section of it to slowly enlarge, forming a bulge — an aneurysm.
Atherosclerosis is a slow process, often taking decades to develop. A diet high in cholesterol and fat is a major risk factor for atherosclerosis. Smoking and high blood pressure also can contribute to atherosclerosis and aneurysm formation.

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