Although most people are aware that mental exercises may slow down the progression or forestall dementia symptoms, they do not completely eliminate the risk of Alzheimer's Disease. Another study, which looked at rats who smoked pot, indicated that the decreased inflammation as a result of the pot smoking, eliminated the risk of inflammation which leads to AD (however, whoever heard of rats who smoked pot, and rats don't get AD). So, is there anything which might prevent AD?
Researchers recently discovered a gene, CETP VV, which alters the cholesterol ester transfer protein, which affects the size of both LDL and HDL. In this very small study, people with this gene, not only lived longer, but were free from dementia (including AD). Needless to say, what good would it do to live to be 100 years old, if your mind was gone? Therefore, the results of this study exact promising news for the future.
SOURCES: Barzilai, N. Neurology, Dec. 26, 2006; vol 67: pp 2170-2175. News release, Albert Einstein College of Medicine of Yeshiva University.

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